BDBM50256183 CHEMBL4087037

SMILES: COc1cccc(Nc2cc(nc3CCNC(=O)c23)-c2cc[n+]([O-])cc2)c1

InChI Key: InChIKey=BQSGRKNUYOEQPY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50256183   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50256183 (CHEMBL4087037) Show SMILES COc1cccc(Nc2cc(nc3CCNC(=O)c23)-c2cc[n+]([O-])cc2)c1 Show InChI InChI=1S/C20H18N4O3/c1-27-15-4-2-3-14(11-15)22-18-12-17(13-6-9-24(26)10-7-13)23-16-5-8-21-20(25)19(16)18/h2-4,6-7,9-12H,5,8H2,1H3,(H,21,25)(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
Medicinal Chemistry& Screening ,?Pharmacokinetics& Metabolism , and§Experimental Dermatology , Almirall S.A., Centro de Investigación y Desarrollo , Crta. Laureà Miró 408-410 , Sant Feliu de Curated by ChEMBL					Assay Description Inhibition of platelet derived growth factor receptor beta phosphorylation in MG63 cells in the presence of human plasma				J Med Chem 61: 2472-2489 (2018) Article DOI: 10.1021/acs.jmedchem.7b01751 BindingDB Entry DOI: 10.7270/Q2HQ42BB
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