BDBM50256186 CHEMBL4093279

SMILES: OCc1cccc(Nc2cc(nc3CCNC(=O)c23)-c2ccccc2)c1

InChI Key: InChIKey=XMOMDSOSOPPNHY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50256186   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50256186 (CHEMBL4093279) Show SMILES OCc1cccc(Nc2cc(nc3CCNC(=O)c23)-c2ccccc2)c1 Show InChI InChI=1S/C21H19N3O2/c25-13-14-5-4-8-16(11-14)23-19-12-18(15-6-2-1-3-7-15)24-17-9-10-22-21(26)20(17)19/h1-8,11-12,25H,9-10,13H2,(H,22,26)(H,23,24)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Medicinal Chemistry& Screening ,?Pharmacokinetics& Metabolism , and§Experimental Dermatology , Almirall S.A., Centro de Investigación y Desarrollo , Crta. Laureà Miró 408-410 , Sant Feliu de Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasma				J Med Chem 61: 2472-2489 (2018) Article DOI: 10.1021/acs.jmedchem.7b01751 BindingDB Entry DOI: 10.7270/Q2HQ42BB
					More data for this Ligand-Target Pair