BDBM50257005 3-[4-(Methylsulfonyl)phenoxy]-N-(4-methyl-1,3-thiazol-2-yl)-5-phenoxybenzamide::CHEMBL483818

SMILES: Cc1csc(NC(=O)c2cc(Oc3ccccc3)cc(Oc3ccc(cc3)S(C)(=O)=O)c2)n1

InChI Key: InChIKey=KHTKOMCOPPNVRX-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50257005   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hexokinase-4 (Homo sapiens (Human))	BDBM50257005 (3-[4-(Methylsulfonyl)phenoxy]-N-(4-methyl-1,3-thia...) Show SMILES Cc1csc(NC(=O)c2cc(Oc3ccccc3)cc(Oc3ccc(cc3)S(C)(=O)=O)c2)n1 Show InChI InChI=1S/C24H20N2O5S2/c1-16-15-32-24(25-16)26-23(27)17-12-20(30-18-6-4-3-5-7-18)14-21(13-17)31-19-8-10-22(11-9-19)33(2,28)29/h3-15H,1-2H3,(H,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	350	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Activation of flag-tagged human recombinant liver glucokinase expressed in Escherichia coli by glucose-6-phosphate dehydrogenase coupled continuous s...				Bioorg Med Chem 17: 2733-43 (2009) Article DOI: 10.1016/j.bmc.2009.02.038 BindingDB Entry DOI: 10.7270/Q2NV9J4Z
					More data for this Ligand-Target Pair
Hexokinase-4 (Homo sapiens (Human))	BDBM50257005 (3-[4-(Methylsulfonyl)phenoxy]-N-(4-methyl-1,3-thia...) Show SMILES Cc1csc(NC(=O)c2cc(Oc3ccccc3)cc(Oc3ccc(cc3)S(C)(=O)=O)c2)n1 Show InChI InChI=1S/C24H20N2O5S2/c1-16-15-32-24(25-16)26-23(27)17-12-20(30-18-6-4-3-5-7-18)14-21(13-17)31-19-8-10-22(11-9-19)33(2,28)29/h3-15H,1-2H3,(H,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	420	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Activation of flag-tagged human recombinant liver glucokinase expressed in Escherichia coli by glucose-6-phosphate dehydrogenase coupled continuous s...				Bioorg Med Chem 17: 2733-43 (2009) Article DOI: 10.1016/j.bmc.2009.02.038 BindingDB Entry DOI: 10.7270/Q2NV9J4Z
					More data for this Ligand-Target Pair