BDBM50257302 2-(1-{3-[6-(Furan-3-carbonyl)-1-propyl-naphthalen-2-yloxy]-propyl}-1H-indol-5-yloxy)-2-methylpropionicacid::CHEMBL522366

SMILES: CCCc1c(OCCCn2ccc3cc(OC(C)(C)C(O)=O)ccc23)ccc2cc(ccc12)C(=O)c1ccoc1

InChI Key: InChIKey=PJYNONFDCUUQAK-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50257302   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50257302 (2-(1-{3-[6-(Furan-3-carbonyl)-1-propyl-naphthalen-...) Show SMILES CCCc1c(OCCCn2ccc3cc(OC(C)(C)C(O)=O)ccc23)ccc2cc(ccc12)C(=O)c1ccoc1 Show InChI InChI=1S/C33H33NO6/c1-4-6-28-27-10-7-24(31(35)25-14-18-38-21-25)19-22(27)8-12-30(28)39-17-5-15-34-16-13-23-20-26(9-11-29(23)34)40-33(2,3)32(36)37/h7-14,16,18-21H,4-6,15,17H2,1-3H3,(H,36,37)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	130	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Agonist activity at human PPARalpha receptor by cell based transactivation assay				J Med Chem 52: 2618-22 (2009) Article DOI: 10.1021/jm801594x BindingDB Entry DOI: 10.7270/Q2SJ1KGZ
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50257302 (2-(1-{3-[6-(Furan-3-carbonyl)-1-propyl-naphthalen-...) Show SMILES CCCc1c(OCCCn2ccc3cc(OC(C)(C)C(O)=O)ccc23)ccc2cc(ccc12)C(=O)c1ccoc1 Show InChI InChI=1S/C33H33NO6/c1-4-6-28-27-10-7-24(31(35)25-14-18-38-21-25)19-22(27)8-12-30(28)39-17-5-15-34-16-13-23-20-26(9-11-29(23)34)40-33(2,3)32(36)37/h7-14,16,18-21H,4-6,15,17H2,1-3H3,(H,36,37)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Agonist activity at human PPARdelta receptor by cell based transactivation assay				J Med Chem 52: 2618-22 (2009) Article DOI: 10.1021/jm801594x BindingDB Entry DOI: 10.7270/Q2SJ1KGZ
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50257302 (2-(1-{3-[6-(Furan-3-carbonyl)-1-propyl-naphthalen-...) Show SMILES CCCc1c(OCCCn2ccc3cc(OC(C)(C)C(O)=O)ccc23)ccc2cc(ccc12)C(=O)c1ccoc1 Show InChI InChI=1S/C33H33NO6/c1-4-6-28-27-10-7-24(31(35)25-14-18-38-21-25)19-22(27)8-12-30(28)39-17-5-15-34-16-13-23-20-26(9-11-29(23)34)40-33(2,3)32(36)37/h7-14,16,18-21H,4-6,15,17H2,1-3H3,(H,36,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	430	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma receptor by cell based transactivation assay				J Med Chem 52: 2618-22 (2009) Article DOI: 10.1021/jm801594x BindingDB Entry DOI: 10.7270/Q2SJ1KGZ
					More data for this Ligand-Target Pair