BDBM50257665 (S)-3-amino-N-(3-(N-(3-(3-carbamimidoylphenyl)-1-(4-methylpiperidin-1-yl)-1-oxopropan-2-yl)sulfamoyl)phenyl)propanamide::CHEMBL493520

SMILES: CC1CCN(CC1)C(=O)[C@H](Cc1cccc(c1)C(N)=N)NS(=O)(=O)c1cccc(NC(=O)CCN)c1

InChI Key: InChIKey=DIJNMZDNCSWBBP-QFIPXVFZSA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50257665   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor activator/Serine protease hepsin/Suppressor of tumorigenicity 14 protein (Homo sapiens (Human))	BDBM50257665 ((S)-3-amino-N-(3-(N-(3-(3-carbamimidoylphenyl)-1-(...) Show SMILES CC1CCN(CC1)C(=O)[C@H](Cc1cccc(c1)C(N)=N)NS(=O)(=O)c1cccc(NC(=O)CCN)c1 |r| Show InChI InChI=1S/C25H34N6O4S/c1-17-9-12-31(13-10-17)25(33)22(15-18-4-2-5-19(14-18)24(27)28)30-36(34,35)21-7-3-6-20(16-21)29-23(32)8-11-26/h2-7,14,16-17,22,30H,8-13,15,26H2,1H3,(H3,27,28)(H,29,32)/t22-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Medicines Company (Leipzig) GmbH Curated by ChEMBL					Assay Description Inhibition of matriptase (unknown origin)				Bioorg Med Chem Lett 19: 1960-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.047 BindingDB Entry DOI: 10.7270/Q2J96681
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50257665 ((S)-3-amino-N-(3-(N-(3-(3-carbamimidoylphenyl)-1-(...) Show SMILES CC1CCN(CC1)C(=O)[C@H](Cc1cccc(c1)C(N)=N)NS(=O)(=O)c1cccc(NC(=O)CCN)c1 |r| Show InChI InChI=1S/C25H34N6O4S/c1-17-9-12-31(13-10-17)25(33)22(15-18-4-2-5-19(14-18)24(27)28)30-36(34,35)21-7-3-6-20(16-21)29-23(32)8-11-26/h2-7,14,16-17,22,30H,8-13,15,26H2,1H3,(H3,27,28)(H,29,32)/t22-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Medicines Company (Leipzig) GmbH Curated by ChEMBL					Assay Description Inhibition of thrombin (unknown origin)				Bioorg Med Chem Lett 19: 1960-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.047 BindingDB Entry DOI: 10.7270/Q2J96681
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50257665 ((S)-3-amino-N-(3-(N-(3-(3-carbamimidoylphenyl)-1-(...) Show SMILES CC1CCN(CC1)C(=O)[C@H](Cc1cccc(c1)C(N)=N)NS(=O)(=O)c1cccc(NC(=O)CCN)c1 |r| Show InChI InChI=1S/C25H34N6O4S/c1-17-9-12-31(13-10-17)25(33)22(15-18-4-2-5-19(14-18)24(27)28)30-36(34,35)21-7-3-6-20(16-21)29-23(32)8-11-26/h2-7,14,16-17,22,30H,8-13,15,26H2,1H3,(H3,27,28)(H,29,32)/t22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Medicines Company (Leipzig) GmbH Curated by ChEMBL					Assay Description Inhibition of uPA (unknown origin)				Bioorg Med Chem Lett 19: 1960-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.047 BindingDB Entry DOI: 10.7270/Q2J96681
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50257665 ((S)-3-amino-N-(3-(N-(3-(3-carbamimidoylphenyl)-1-(...) Show SMILES CC1CCN(CC1)C(=O)[C@H](Cc1cccc(c1)C(N)=N)NS(=O)(=O)c1cccc(NC(=O)CCN)c1 |r| Show InChI InChI=1S/C25H34N6O4S/c1-17-9-12-31(13-10-17)25(33)22(15-18-4-2-5-19(14-18)24(27)28)30-36(34,35)21-7-3-6-20(16-21)29-23(32)8-11-26/h2-7,14,16-17,22,30H,8-13,15,26H2,1H3,(H3,27,28)(H,29,32)/t22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Medicines Company (Leipzig) GmbH Curated by ChEMBL					Assay Description Inhibition of factor 10a (unknown origin)				Bioorg Med Chem Lett 19: 1960-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.047 BindingDB Entry DOI: 10.7270/Q2J96681
					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM50257665 ((S)-3-amino-N-(3-(N-(3-(3-carbamimidoylphenyl)-1-(...) Show SMILES CC1CCN(CC1)C(=O)[C@H](Cc1cccc(c1)C(N)=N)NS(=O)(=O)c1cccc(NC(=O)CCN)c1 |r| Show InChI InChI=1S/C25H34N6O4S/c1-17-9-12-31(13-10-17)25(33)22(15-18-4-2-5-19(14-18)24(27)28)30-36(34,35)21-7-3-6-20(16-21)29-23(32)8-11-26/h2-7,14,16-17,22,30H,8-13,15,26H2,1H3,(H3,27,28)(H,29,32)/t22-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Medicines Company (Leipzig) GmbH Curated by ChEMBL					Assay Description Inhibition of plasmin (unknown origin)				Bioorg Med Chem Lett 19: 1960-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.047 BindingDB Entry DOI: 10.7270/Q2J96681
					More data for this Ligand-Target Pair