BDBM50257666 (S)-3-amino-N-(3-(N-(1-(4-benzylpiperidin-1-yl)-3-(3-carbamimidoylphenyl)-1-oxopropan-2-yl)sulfamoyl)phenyl)propanamide::CHEMBL445195

SMILES: NCCC(=O)Nc1cccc(c1)S(=O)(=O)N[C@@H](Cc1cccc(c1)C(N)=N)C(=O)N1CCC(Cc2ccccc2)CC1

InChI Key: InChIKey=HPNPGMUJDLURDV-NDEPHWFRSA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50257666   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor activator/Serine protease hepsin/Suppressor of tumorigenicity 14 protein (Homo sapiens (Human))	BDBM50257666 ((S)-3-amino-N-(3-(N-(1-(4-benzylpiperidin-1-yl)-3-...) Show SMILES NCCC(=O)Nc1cccc(c1)S(=O)(=O)N[C@@H](Cc1cccc(c1)C(N)=N)C(=O)N1CCC(Cc2ccccc2)CC1 |r| Show InChI InChI=1S/C31H38N6O4S/c32-15-12-29(38)35-26-10-5-11-27(21-26)42(40,41)36-28(20-24-8-4-9-25(19-24)30(33)34)31(39)37-16-13-23(14-17-37)18-22-6-2-1-3-7-22/h1-11,19,21,23,28,36H,12-18,20,32H2,(H3,33,34)(H,35,38)/t28-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Medicines Company (Leipzig) GmbH Curated by ChEMBL					Assay Description Inhibition of matriptase (unknown origin)				Bioorg Med Chem Lett 19: 1960-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.047 BindingDB Entry DOI: 10.7270/Q2J96681
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50257666 ((S)-3-amino-N-(3-(N-(1-(4-benzylpiperidin-1-yl)-3-...) Show SMILES NCCC(=O)Nc1cccc(c1)S(=O)(=O)N[C@@H](Cc1cccc(c1)C(N)=N)C(=O)N1CCC(Cc2ccccc2)CC1 |r| Show InChI InChI=1S/C31H38N6O4S/c32-15-12-29(38)35-26-10-5-11-27(21-26)42(40,41)36-28(20-24-8-4-9-25(19-24)30(33)34)31(39)37-16-13-23(14-17-37)18-22-6-2-1-3-7-22/h1-11,19,21,23,28,36H,12-18,20,32H2,(H3,33,34)(H,35,38)/t28-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Medicines Company (Leipzig) GmbH Curated by ChEMBL					Assay Description Inhibition of thrombin (unknown origin)				Bioorg Med Chem Lett 19: 1960-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.047 BindingDB Entry DOI: 10.7270/Q2J96681
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50257666 ((S)-3-amino-N-(3-(N-(1-(4-benzylpiperidin-1-yl)-3-...) Show SMILES NCCC(=O)Nc1cccc(c1)S(=O)(=O)N[C@@H](Cc1cccc(c1)C(N)=N)C(=O)N1CCC(Cc2ccccc2)CC1 |r| Show InChI InChI=1S/C31H38N6O4S/c32-15-12-29(38)35-26-10-5-11-27(21-26)42(40,41)36-28(20-24-8-4-9-25(19-24)30(33)34)31(39)37-16-13-23(14-17-37)18-22-6-2-1-3-7-22/h1-11,19,21,23,28,36H,12-18,20,32H2,(H3,33,34)(H,35,38)/t28-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Medicines Company (Leipzig) GmbH Curated by ChEMBL					Assay Description Inhibition of uPA (unknown origin)				Bioorg Med Chem Lett 19: 1960-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.047 BindingDB Entry DOI: 10.7270/Q2J96681
					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM50257666 ((S)-3-amino-N-(3-(N-(1-(4-benzylpiperidin-1-yl)-3-...) Show SMILES NCCC(=O)Nc1cccc(c1)S(=O)(=O)N[C@@H](Cc1cccc(c1)C(N)=N)C(=O)N1CCC(Cc2ccccc2)CC1 |r| Show InChI InChI=1S/C31H38N6O4S/c32-15-12-29(38)35-26-10-5-11-27(21-26)42(40,41)36-28(20-24-8-4-9-25(19-24)30(33)34)31(39)37-16-13-23(14-17-37)18-22-6-2-1-3-7-22/h1-11,19,21,23,28,36H,12-18,20,32H2,(H3,33,34)(H,35,38)/t28-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Medicines Company (Leipzig) GmbH Curated by ChEMBL					Assay Description Inhibition of plasmin (unknown origin)				Bioorg Med Chem Lett 19: 1960-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.047 BindingDB Entry DOI: 10.7270/Q2J96681
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50257666 ((S)-3-amino-N-(3-(N-(1-(4-benzylpiperidin-1-yl)-3-...) Show SMILES NCCC(=O)Nc1cccc(c1)S(=O)(=O)N[C@@H](Cc1cccc(c1)C(N)=N)C(=O)N1CCC(Cc2ccccc2)CC1 |r| Show InChI InChI=1S/C31H38N6O4S/c32-15-12-29(38)35-26-10-5-11-27(21-26)42(40,41)36-28(20-24-8-4-9-25(19-24)30(33)34)31(39)37-16-13-23(14-17-37)18-22-6-2-1-3-7-22/h1-11,19,21,23,28,36H,12-18,20,32H2,(H3,33,34)(H,35,38)/t28-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Medicines Company (Leipzig) GmbH Curated by ChEMBL					Assay Description Inhibition of factor 10a (unknown origin)				Bioorg Med Chem Lett 19: 1960-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.047 BindingDB Entry DOI: 10.7270/Q2J96681
					More data for this Ligand-Target Pair