Found 5 hits for monomerid = 50257706 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Hepatocyte growth factor activator/Serine protease hepsin/Suppressor of tumorigenicity 14 protein
(Homo sapiens (Human)) | BDBM50257706
((S)-3-amino-N-(3-(N-(3-(3-carbamimidoylphenyl)-1-(...)Show SMILES NCCC(=O)Nc1cccc(c1)S(=O)(=O)N[C@@H](Cc1cccc(c1)C(N)=N)C(=O)N1CCN(CC1)c1ccc(O)cc1 |r| Show InChI InChI=1S/C29H35N7O5S/c30-12-11-27(38)33-22-5-2-6-25(19-22)42(40,41)34-26(18-20-3-1-4-21(17-20)28(31)32)29(39)36-15-13-35(14-16-36)23-7-9-24(37)10-8-23/h1-10,17,19,26,34,37H,11-16,18,30H2,(H3,31,32)(H,33,38)/t26-/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Medicines Company (Leipzig) GmbH
Curated by ChEMBL
| Assay Description Inhibition of matriptase (unknown origin) |
Bioorg Med Chem Lett 19: 1960-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.047 BindingDB Entry DOI: 10.7270/Q2J96681 |
More data for this Ligand-Target Pair | |
Plasminogen
(Homo sapiens (Human)) | BDBM50257706
((S)-3-amino-N-(3-(N-(3-(3-carbamimidoylphenyl)-1-(...)Show SMILES NCCC(=O)Nc1cccc(c1)S(=O)(=O)N[C@@H](Cc1cccc(c1)C(N)=N)C(=O)N1CCN(CC1)c1ccc(O)cc1 |r| Show InChI InChI=1S/C29H35N7O5S/c30-12-11-27(38)33-22-5-2-6-25(19-22)42(40,41)34-26(18-20-3-1-4-21(17-20)28(31)32)29(39)36-15-13-35(14-16-36)23-7-9-24(37)10-8-23/h1-10,17,19,26,34,37H,11-16,18,30H2,(H3,31,32)(H,33,38)/t26-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Medicines Company (Leipzig) GmbH
Curated by ChEMBL
| Assay Description Inhibition of plasmin (unknown origin) |
Bioorg Med Chem Lett 19: 1960-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.047 BindingDB Entry DOI: 10.7270/Q2J96681 |
More data for this Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50257706
((S)-3-amino-N-(3-(N-(3-(3-carbamimidoylphenyl)-1-(...)Show SMILES NCCC(=O)Nc1cccc(c1)S(=O)(=O)N[C@@H](Cc1cccc(c1)C(N)=N)C(=O)N1CCN(CC1)c1ccc(O)cc1 |r| Show InChI InChI=1S/C29H35N7O5S/c30-12-11-27(38)33-22-5-2-6-25(19-22)42(40,41)34-26(18-20-3-1-4-21(17-20)28(31)32)29(39)36-15-13-35(14-16-36)23-7-9-24(37)10-8-23/h1-10,17,19,26,34,37H,11-16,18,30H2,(H3,31,32)(H,33,38)/t26-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Medicines Company (Leipzig) GmbH
Curated by ChEMBL
| Assay Description Inhibition of factor 10a (unknown origin) |
Bioorg Med Chem Lett 19: 1960-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.047 BindingDB Entry DOI: 10.7270/Q2J96681 |
More data for this Ligand-Target Pair | |
Urokinase-type plasminogen activator
(Homo sapiens (Human)) | BDBM50257706
((S)-3-amino-N-(3-(N-(3-(3-carbamimidoylphenyl)-1-(...)Show SMILES NCCC(=O)Nc1cccc(c1)S(=O)(=O)N[C@@H](Cc1cccc(c1)C(N)=N)C(=O)N1CCN(CC1)c1ccc(O)cc1 |r| Show InChI InChI=1S/C29H35N7O5S/c30-12-11-27(38)33-22-5-2-6-25(19-22)42(40,41)34-26(18-20-3-1-4-21(17-20)28(31)32)29(39)36-15-13-35(14-16-36)23-7-9-24(37)10-8-23/h1-10,17,19,26,34,37H,11-16,18,30H2,(H3,31,32)(H,33,38)/t26-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 8.37E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Medicines Company (Leipzig) GmbH
Curated by ChEMBL
| Assay Description Inhibition of uPA (unknown origin) |
Bioorg Med Chem Lett 19: 1960-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.047 BindingDB Entry DOI: 10.7270/Q2J96681 |
More data for this Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50257706
((S)-3-amino-N-(3-(N-(3-(3-carbamimidoylphenyl)-1-(...)Show SMILES NCCC(=O)Nc1cccc(c1)S(=O)(=O)N[C@@H](Cc1cccc(c1)C(N)=N)C(=O)N1CCN(CC1)c1ccc(O)cc1 |r| Show InChI InChI=1S/C29H35N7O5S/c30-12-11-27(38)33-22-5-2-6-25(19-22)42(40,41)34-26(18-20-3-1-4-21(17-20)28(31)32)29(39)36-15-13-35(14-16-36)23-7-9-24(37)10-8-23/h1-10,17,19,26,34,37H,11-16,18,30H2,(H3,31,32)(H,33,38)/t26-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.45E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Medicines Company (Leipzig) GmbH
Curated by ChEMBL
| Assay Description Inhibition of thrombin (unknown origin) |
Bioorg Med Chem Lett 19: 1960-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.047 BindingDB Entry DOI: 10.7270/Q2J96681 |
More data for this Ligand-Target Pair | |