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SMILES: Nc1ccnc(c1)N1CCC2(CC1)OCc1ccccc21

InChI Key: InChIKey=MGQVSVUXSCNPLN-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50257721   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Delta-type opioid receptor


(Homo sapiens (Human))		BDBM50257721
PNG
(2-(3H-spiro[isobenzofuran-1,4'-piperidine]-1'-yl)p...)
Show SMILES Nc1ccnc(c1)N1CCC2(CC1)OCc1ccccc21
Show InChI InChI=1S/C17H19N3O/c18-14-5-8-19-16(11-14)20-9-6-17(7-10-20)15-4-2-1-3-13(15)12-21-17/h1-5,8,11H,6-7,9-10,12H2,(H2,18,19)
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Article
PubMed
n/an/an/an/a 308n/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Agonist activity at delta opioid receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production by ALPHAscreen assay

Bioorg Med Chem Lett 19: 1702-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.106
BindingDB Entry DOI: 10.7270/Q21G0M40
More data for this
Ligand-Target Pair