BDBM50257726 2'-hydroxy-3,4,5-trimethoxychalcone::CHEMBL521653

SMILES: COc1cc(\C=C\C(=O)c2ccccc2O)cc(OC)c1OC

InChI Key: InChIKey=SRSBUHVXNLHWHU-CMDGGOBGSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50257726   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclooxygenase-2 (COX-2) (Mus musculus (Mouse))	BDBM50257726 (2'-hydroxy-3,4,5-trimethoxychalcone | CHEMBL521653) Show SMILES COc1cc(\C=C\C(=O)c2ccccc2O)cc(OC)c1OC Show InChI InChI=1S/C18H18O5/c1-21-16-10-12(11-17(22-2)18(16)23-3)8-9-15(20)13-6-4-5-7-14(13)19/h4-11,19H,1-3H3/b9-8+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Medicine and Pharmacy at Ho Chi Minh City Curated by ChEMBL					Assay Description Inhibition of COX2-mediated PGE2 production in LPS-stimulated mouse RAW264.7 cells by enzyme immunoassay				Bioorg Med Chem Lett 19: 1650-3 (2009) Article DOI: 10.1016/j.bmcl.2009.02.001 BindingDB Entry DOI: 10.7270/Q28052HJ
					More data for this Ligand-Target Pair