BDBM50257945 CHEMBL493997::methyl 3-(4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imidazol-2-yl)benzoate

SMILES: COC(=O)c1cccc(c1)C1=NC(CN1)(c1ccc(F)cc1)c1ccc(F)cc1

InChI Key: InChIKey=MEJLXFKXHDIKGE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50257945   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 5 ( NPY Y5) (Homo sapiens (Human))	BDBM50257945 (CHEMBL493997 | methyl 3-(4,4-bis(4-fluorophenyl)-4...) Show SMILES COC(=O)c1cccc(c1)C1=NC(CN1)(c1ccc(F)cc1)c1ccc(F)cc1 |t:11| Show InChI InChI=1S/C23H18F2N2O2/c1-29-22(28)16-4-2-3-15(13-16)21-26-14-23(27-21,17-5-9-19(24)10-6-17)18-7-11-20(25)12-8-18/h2-13H,14H2,1H3,(H,26,27)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase-deficient mouse LM cells				Bioorg Med Chem Lett 19: 1670-4 (2009) Article DOI: 10.1016/j.bmcl.2009.01.101 BindingDB Entry DOI: 10.7270/Q24749RC
					More data for this Ligand-Target Pair