BDBM50258138 6-(4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imidazol-2-yl)pyridin-2(1H)-one::CHEMBL492377

SMILES: Fc1ccc(cc1)C1(CNC(=N1)c1cccc(=O)[nH]1)c1ccc(F)cc1

InChI Key: InChIKey=WXNATCXWMXDARJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50258138   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 5 ( NPY Y5) (Homo sapiens (Human))	BDBM50258138 (6-(4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imidazol...) Show SMILES Fc1ccc(cc1)C1(CNC(=N1)c1cccc(=O)[nH]1)c1ccc(F)cc1 |c:11| Show InChI InChI=1S/C20H15F2N3O/c21-15-8-4-13(5-9-15)20(14-6-10-16(22)11-7-14)12-23-19(25-20)17-2-1-3-18(26)24-17/h1-11H,12H2,(H,23,25)(H,24,26)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.10	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase-deficient mouse LM cells				Bioorg Med Chem Lett 19: 1670-4 (2009) Article DOI: 10.1016/j.bmcl.2009.01.101 BindingDB Entry DOI: 10.7270/Q24749RC
					More data for this Ligand-Target Pair