BDBM50258343 5-(3,4-dimethoxyphenyl)-4-(1H-indol-5-yl)nicotinonitrile::CHEMBL494238
SMILES: COc1ccc(cc1OC)-c1cncc(C#N)c1-c1ccc2[nH]ccc2c1
InChI Key: InChIKey=JXNLOQFXGXDNAK-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Protein kinase C theta type (Homo sapiens (Human)) | BDBM50258343 (5-(3,4-dimethoxyphenyl)-4-(1H-indol-5-yl)nicotinon...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Inhibition of human PKCtheta by IMAP assay | Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4 | |||||||||||
More data for this Ligand-Target Pair |