BDBM50258345 5-(4-(2-(4-(2-hydroxyethyl)piperazin-1-yl)ethoxy)phenyl)-4-(4-methyl-1H-indol-5-ylamino)nicotinonitrile::CHEMBL522344

SMILES: Cc1c(Nc2c(cncc2-c2ccc(OCCN3CCN(CCO)CC3)cc2)C#N)ccc2[nH]ccc12

InChI Key: InChIKey=IFPLUMSPGLKAOT-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50258345   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C delta type (Homo sapiens (Human))	BDBM50258345 (5-(4-(2-(4-(2-hydroxyethyl)piperazin-1-yl)ethoxy)p...) Show SMILES Cc1c(Nc2c(cncc2-c2ccc(OCCN3CCN(CCO)CC3)cc2)C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C29H32N6O2/c1-21-25-8-9-32-28(25)7-6-27(21)33-29-23(18-30)19-31-20-26(29)22-2-4-24(5-3-22)37-17-15-35-12-10-34(11-13-35)14-16-36/h2-9,19-20,32,36H,10-17H2,1H3,(H,31,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCdelta by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50258345 (5-(4-(2-(4-(2-hydroxyethyl)piperazin-1-yl)ethoxy)p...) Show SMILES Cc1c(Nc2c(cncc2-c2ccc(OCCN3CCN(CCO)CC3)cc2)C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C29H32N6O2/c1-21-25-8-9-32-28(25)7-6-27(21)33-29-23(18-30)19-31-20-26(29)22-2-4-24(5-3-22)37-17-15-35-12-10-34(11-13-35)14-16-36/h2-9,19-20,32,36H,10-17H2,1H3,(H,31,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCtheta by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair