BDBM50258348 CHEMBL4073071

SMILES: NC(=O)C(=O)C(Cc1ccccc1)NC(=O)c1ccccc1-c1csc(n1)-c1ccccc1

InChI Key: InChIKey=LFZBGLILWDTWBK-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50258348   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calpain1 (Homo sapiens (Human))	BDBM50258348 (CHEMBL4073071) Show SMILES NC(=O)C(=O)C(Cc1ccccc1)NC(=O)c1ccccc1-c1csc(n1)-c1ccccc1 Show InChI InChI=1S/C26H21N3O3S/c27-24(31)23(30)21(15-17-9-3-1-4-10-17)28-25(32)20-14-8-7-13-19(20)22-16-33-26(29-22)18-11-5-2-6-12-18/h1-14,16,21H,15H2,(H2,27,31)(H,28,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	82	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neuroscience Research, AbbVie Deutschland GmbH& Co. KG , Knollstrasse, 67061 Ludwigshafen, Germany. Curated by ChEMBL					Assay Description Inhibition of human erythrocytes calpain-1 using Suc-Leu-Tyr-AMC as substrate by kinetic fluorescence assay				J Med Chem 60: 7123-7138 (2017) Article DOI: 10.1021/acs.jmedchem.7b00731 BindingDB Entry DOI: 10.7270/Q2Q242P4
					More data for this Ligand-Target Pair