BDBM50258386 5-(3,4-dimethoxyphenyl)-4-(7-methyl-1H-indol-5-ylamino)nicotinonitrile::CHEMBL494001

SMILES: COc1ccc(cc1OC)-c1cncc(C#N)c1Nc1cc(C)c2[nH]ccc2c1

InChI Key: InChIKey=IZWBUZBLTONUFH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50258386   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C theta type (Homo sapiens (Human))	BDBM50258386 (5-(3,4-dimethoxyphenyl)-4-(7-methyl-1H-indol-5-yla...) Show SMILES COc1ccc(cc1OC)-c1cncc(C#N)c1Nc1cc(C)c2[nH]ccc2c1 Show InChI InChI=1S/C23H20N4O2/c1-14-8-18(9-16-6-7-26-22(14)16)27-23-17(11-24)12-25-13-19(23)15-4-5-20(28-2)21(10-15)29-3/h4-10,12-13,26H,1-3H3,(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCtheta by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair