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SMILES: CC(C)(C)c1cc2CCCOc2c(\C=C\C(=O)NCc2ccc(NS(C)(=O)=O)c(F)c2)c1

InChI Key: InChIKey=VNWYSBBCZHIUIE-CSKARUKUSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50258445   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Rattus norvegicus (rat))		BDBM50258445
PNG
((E)-3-(6-tert-Butylchroman-8-yl)-N-(3-fluoro-4-(me...)
Show SMILES CC(C)(C)c1cc2CCCOc2c(\C=C\C(=O)NCc2ccc(NS(C)(=O)=O)c(F)c2)c1
Show InChI InChI=1S/C24H29FN2O4S/c1-24(2,3)19-13-17-6-5-11-31-23(17)18(14-19)8-10-22(28)26-15-16-7-9-21(20(25)12-16)27-32(4,29)30/h7-10,12-14,27H,5-6,11,15H2,1-4H3,(H,26,28)/b10-8+
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Article
PubMed
n/an/a 920n/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
Antagonist activity at TRPV1 in Sprague-Dawley rat DRG neuron assessed as reduction of capsaicin-stimulated 45Ca2+ uptake

Bioorg Med Chem 17: 3557-67 (2009)


Article DOI: 10.1016/j.bmc.2009.04.010
BindingDB Entry DOI: 10.7270/Q2V124QJ
More data for this
Ligand-Target Pair