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SMILES: CC1(C)CCc2cc(\C=C\C(=O)NCc3ccc(NS(C)(=O)=O)c(F)c3)ccc2O1

InChI Key: InChIKey=OGMUQWIGCUMXCQ-RMKNXTFCSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50258474   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Rattus norvegicus (rat))		BDBM50258474
PNG
((E)-3-(2,2-Dimethylchroman-6-yl)-N-(3-fluoro-4-(me...)
Show SMILES CC1(C)CCc2cc(\C=C\C(=O)NCc3ccc(NS(C)(=O)=O)c(F)c3)ccc2O1
Show InChI InChI=1S/C22H25FN2O4S/c1-22(2)11-10-17-12-15(5-8-20(17)29-22)6-9-21(26)24-14-16-4-7-19(18(23)13-16)25-30(3,27)28/h4-9,12-13,25H,10-11,14H2,1-3H3,(H,24,26)/b9-6+
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MMDB

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Similars
Article
PubMed
n/an/a 1.40E+3n/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
Antagonist activity at TRPV1 in Sprague-Dawley rat DRG neuron assessed as reduction of capsaicin-stimulated 45Ca2+ uptake

Bioorg Med Chem 17: 3557-67 (2009)


Article DOI: 10.1016/j.bmc.2009.04.010
BindingDB Entry DOI: 10.7270/Q2V124QJ
More data for this
Ligand-Target Pair