BDBM50258609 4,7-dichloro-1-(3-methoxybenzyl)indoline-2,3-dione::CHEMBL513311

SMILES: COc1cccc(CN2C(=O)C(=O)c3c2c(Cl)ccc3Cl)c1

InChI Key: InChIKey=NPOMIKJMXRXVAI-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50258609   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50258609 (4,7-dichloro-1-(3-methoxybenzyl)indoline-2,3-dione...) Show SMILES COc1cccc(CN2C(=O)C(=O)c3c2c(Cl)ccc3Cl)c1 Show InChI InChI=1S/C16H11Cl2NO3/c1-22-10-4-2-3-9(7-10)8-19-14-12(18)6-5-11(17)13(14)15(20)16(19)21/h2-7H,8H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.15E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Activation of human muscarinic M5 receptor expressed in CHO cells coexpressing Gq protein assessed as potentiation of acetylcholine-induced intracell...				J Med Chem 52: 3445-8 (2009) Article DOI: 10.1021/jm900286j BindingDB Entry DOI: 10.7270/Q23B601Q
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50258609 (4,7-dichloro-1-(3-methoxybenzyl)indoline-2,3-dione...) Show SMILES COc1cccc(CN2C(=O)C(=O)c3c2c(Cl)ccc3Cl)c1 Show InChI InChI=1S/C16H11Cl2NO3/c1-22-10-4-2-3-9(7-10)8-19-14-12(18)6-5-11(17)13(14)15(20)16(19)21/h2-7H,8H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Activation of rat muscarinic M1 receptor expressed in CHO cells coexpressing Gq protein assessed as potentiation of acetylcholine-induced intracellul...				J Med Chem 52: 3445-8 (2009) Article DOI: 10.1021/jm900286j BindingDB Entry DOI: 10.7270/Q23B601Q
					More data for this Ligand-Target Pair