BDBM50258838 (E)-N-(3-Fluoro-4-(methylsulfonamido)benzyl)-3-(4-iodophenyl)acrylmide::CHEMBL449000

SMILES: CS(=O)(=O)Nc1ccc(CNC(=O)\C=C\c2ccc(I)cc2)cc1F

InChI Key: InChIKey=KLOPICDADCEBGF-WEVVVXLNSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50258838   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vanilloid receptor (Rattus norvegicus (rat))	BDBM50258838 ((E)-N-(3-Fluoro-4-(methylsulfonamido)benzyl)-3-(4-...) Show SMILES CS(=O)(=O)Nc1ccc(CNC(=O)\C=C\c2ccc(I)cc2)cc1F Show InChI InChI=1S/C17H16FIN2O3S/c1-25(23,24)21-16-8-4-13(10-15(16)18)11-20-17(22)9-5-12-2-6-14(19)7-3-12/h2-10,21H,11H2,1H3,(H,20,22)/b9-5+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonist activity at TRPV1 in Sprague-Dawley rat DRG neuron assessed as reduction of capsaicin-stimulated 45Ca2+ uptake				Bioorg Med Chem 17: 3557-67 (2009) Article DOI: 10.1016/j.bmc.2009.04.010 BindingDB Entry DOI: 10.7270/Q2V124QJ
					More data for this Ligand-Target Pair