BDBM50259705 CHEMBL4088638
SMILES: CCN(CC)CCCNC(=O)c1ccc(o1)[N+]([O-])=O
InChI Key: InChIKey=DKWGBKJZAAPJOE-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Trypanothione reductase (Trypanosoma cruzi) | BDBM50259705![]() (CHEMBL4088638) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 1.28E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Nacional del Litoral Curated by ChEMBL | Assay Description Uncompetitive inhibition of Trypanosoma cruzi trypanothione reductase using T(SH)2 as substrate at pH 7.5 in presence of NADPH by photometric method | Eur J Med Chem 125: 1088-1097 (2017) Article DOI: 10.1016/j.ejmech.2016.10.055 BindingDB Entry DOI: 10.7270/Q2TM7DKH | |||||||||||
More data for this Ligand-Target Pair |