BDBM50260331 CHEMBL4088230

SMILES: CC(C)N1CCN(C\C=C\c2ccc(CN(CC(C)(C)C)c3cc(C)nc(C)n3)cc2)CC1

InChI Key: InChIKey=ADLVHQUDPROVIJ-CMDGGOBGSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50260331   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G-protein coupled receptor 4 (Rattus norvegicus)	BDBM50260331 (CHEMBL4088230) Show SMILES CC(C)N1CCN(C\C=C\c2ccc(CN(CC(C)(C)C)c3cc(C)nc(C)n3)cc2)CC1 Show InChI InChI=1S/C28H43N5/c1-22(2)32-17-15-31(16-18-32)14-8-9-25-10-12-26(13-11-25)20-33(21-28(5,6)7)27-19-23(3)29-24(4)30-27/h8-13,19,22H,14-18,20-21H2,1-7H3/b9-8+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.59E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Antagonist activity at rat GPR4 expressed in HEK cells assessed as inhibition of pH-induced cAMP accumulation preincubated for 15 mins followed by cA...				Bioorg Med Chem 25: 4512-4525 (2017) Article DOI: 10.1016/j.bmc.2017.06.050 BindingDB Entry DOI: 10.7270/Q2NS0XB3
					More data for this Ligand-Target Pair
G-protein coupled receptor 4 (Homo sapiens (Human))	BDBM50260331 (CHEMBL4088230) Show SMILES CC(C)N1CCN(C\C=C\c2ccc(CN(CC(C)(C)C)c3cc(C)nc(C)n3)cc2)CC1 Show InChI InChI=1S/C28H43N5/c1-22(2)32-17-15-31(16-18-32)14-8-9-25-10-12-26(13-11-25)20-33(21-28(5,6)7)27-19-23(3)29-24(4)30-27/h8-13,19,22H,14-18,20-21H2,1-7H3/b9-8+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Antagonist activity at human GPR4 expressed in African green monkey COS7 cells assessed as inhibition of pH 6.5-induced cAMP accumulation after 30 mi...				Bioorg Med Chem 25: 4512-4525 (2017) Article DOI: 10.1016/j.bmc.2017.06.050 BindingDB Entry DOI: 10.7270/Q2NS0XB3
					More data for this Ligand-Target Pair
G-protein coupled receptor 4 (Mus musculus)	BDBM50260331 (CHEMBL4088230) Show SMILES CC(C)N1CCN(C\C=C\c2ccc(CN(CC(C)(C)C)c3cc(C)nc(C)n3)cc2)CC1 Show InChI InChI=1S/C28H43N5/c1-22(2)32-17-15-31(16-18-32)14-8-9-25-10-12-26(13-11-25)20-33(21-28(5,6)7)27-19-23(3)29-24(4)30-27/h8-13,19,22H,14-18,20-21H2,1-7H3/b9-8+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.63E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Antagonist activity at mouse GPR4 expressed in HEK cells assessed as inhibition of pH-induced cAMP accumulation preincubated for 15 mins followed by ...				Bioorg Med Chem 25: 4512-4525 (2017) Article DOI: 10.1016/j.bmc.2017.06.050 BindingDB Entry DOI: 10.7270/Q2NS0XB3
					More data for this Ligand-Target Pair