BDBM50260438 CHEMBL4088975

SMILES: CC(C)C[C@H]1C[C@@H](C)[C@@]2(N1C(=O)c1ccccn1)C(=O)Nc1ccccc21

InChI Key: InChIKey=FQUSMUUUVVIEQL-VVBPWWLESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50260438   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
U5 small nuclear ribonucleoprotein 200 kDa helicase (Homo sapiens (Human))	BDBM50260438 (CHEMBL4088975) Show SMILES CC(C)C[C@H]1C[C@@H](C)[C@@]2(N1C(=O)c1ccccn1)C(=O)Nc1ccccc21 |r| Show InChI InChI=1S/C22H25N3O2/c1-14(2)12-16-13-15(3)22(17-8-4-5-9-18(17)24-21(22)27)25(16)20(26)19-10-6-7-11-23-19/h4-11,14-16H,12-13H2,1-3H3,(H,24,27)/t15-,16+,22+/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of full length recombinant human N-terminal His-tagged BRR2 RNA dependent ATPase activity expressed in baculovirus infected Sf9 cells usin...				Bioorg Med Chem 25: 4753-4767 (2017) Article DOI: 10.1016/j.bmc.2017.07.017 BindingDB Entry DOI: 10.7270/Q27M0BDH
					More data for this Ligand-Target Pair