BDBM50260546 CHEMBL4105153

SMILES: Nc1ccc(-c2c[nH]c3cc(ccc23)-c2cncc(n2)N2CCNCC2)c(F)n1

InChI Key: InChIKey=VCNYZERFJDFBKP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50260546   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50260546 (CHEMBL4105153) Show SMILES Nc1ccc(-c2c[nH]c3cc(ccc23)-c2cncc(n2)N2CCNCC2)c(F)n1 Show InChI InChI=1S/C21H20FN7/c22-21-15(3-4-19(23)28-21)16-10-26-17-9-13(1-2-14(16)17)18-11-25-12-20(27-18)29-7-5-24-6-8-29/h1-4,9-12,24,26H,5-8H2,(H2,23,28)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Zarqa University Curated by ChEMBL					Assay Description Inhibition of human recombinant PIM1 in presence of ATP by ELISA based spectrophotometric analysis				Bioorg Med Chem 25: 4855-4875 (2017) Article DOI: 10.1016/j.bmc.2017.07.036 BindingDB Entry DOI: 10.7270/Q2BC420V
					More data for this Ligand-Target Pair