BDBM50260702 CHEMBL4089536

SMILES: OC(=O)c1cccc(Cc2c(nn3cc(Cl)ccc23)-c2ccccc2)c1

InChI Key: InChIKey=UWMVRDDUAYAKJI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50260702   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostanoid EP1 receptor (Rattus norvegicus (Rat))	BDBM50260702 (CHEMBL4089536) Show SMILES OC(=O)c1cccc(Cc2c(nn3cc(Cl)ccc23)-c2ccccc2)c1 Show InChI InChI=1S/C21H15ClN2O2/c22-17-9-10-19-18(12-14-5-4-8-16(11-14)21(25)26)20(23-24(19)13-17)15-6-2-1-3-7-15/h1-11,13H,12H2,(H,25,26)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Watarase Research Center, Discovery Research Headquarters, Kyorin Pharmaceutical Co., Ltd., 1848, Nogi, Nogi-machi, Shimotsuga-gun, Tochigi 329-0114, Japan. Curated by ChEMBL					Assay Description Antagonist activity at rat His-tagged EP1 receptor expressed in African green monkey COS1 cells assessed as reduction in PGE2-induced increase in int...				Bioorg Med Chem Lett 27: 4044-4050 (2017) Article DOI: 10.1016/j.bmcl.2017.07.055 BindingDB Entry DOI: 10.7270/Q2PN983F
					More data for this Ligand-Target Pair