BDBM50260869 CHEMBL4071815

SMILES: COc1nn(CC(N)=O)c2ncnc(NS(=O)(=O)c3cccc(Cl)c3Cl)c12

InChI Key: InChIKey=OIAUASFAFVUJLY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50260869   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50260869 (CHEMBL4071815) Show SMILES COc1nn(CC(N)=O)c2ncnc(NS(=O)(=O)c3cccc(Cl)c3Cl)c12 Show InChI InChI=1S/C14H12Cl2N6O4S/c1-26-14-10-12(18-6-19-13(10)22(20-14)5-9(17)23)21-27(24,25)8-4-2-3-7(15)11(8)16/h2-4,6H,5H2,1H3,(H2,17,23)(H,18,19,21)	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	501	n/a	n/a	n/a	n/a	n/a	n/a
Department of Medicinal Chemistry, Respiratory TAU, GlaxoSmithKline Medicines Research Centre, Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, United Kingdom. Electronic address: afjal.h.miah@gs Curated by ChEMBL					Assay Description Antagonist activity at human recombinant CCR4 receptor expressed in CHO cell membranes by [35S]GTPgammaS binding assay				Bioorg Med Chem 25: 5327-5340 (2017) Article DOI: 10.1016/j.bmc.2017.07.052 BindingDB Entry DOI: 10.7270/Q2X350X1
					More data for this Ligand-Target Pair