BDBM50260898 CHEMBL4071299

SMILES: COc1nn(C)c2ncnc(NS(=O)(=O)c3ccc(Cl)s3)c12

InChI Key: InChIKey=AWKFPMCWSXXRCE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50260898   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50260898 (CHEMBL4071299) Show SMILES COc1nn(C)c2ncnc(NS(=O)(=O)c3ccc(Cl)s3)c12 Show InChI InChI=1S/C11H10ClN5O3S2/c1-17-10-8(11(15-17)20-2)9(13-5-14-10)16-22(18,19)7-4-3-6(12)21-7/h3-5H,1-2H3,(H,13,14,16)	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	n/a
Department of Medicinal Chemistry, Respiratory TAU, GlaxoSmithKline Medicines Research Centre, Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, United Kingdom. Electronic address: afjal.h.miah@gs Curated by ChEMBL					Assay Description Antagonist activity at human recombinant CCR4 receptor expressed in CHO cell membranes by [35S]GTPgammaS binding assay				Bioorg Med Chem 25: 5327-5340 (2017) Article DOI: 10.1016/j.bmc.2017.07.052 BindingDB Entry DOI: 10.7270/Q2X350X1
					More data for this Ligand-Target Pair