BDBM50260930 CHEMBL4087403

SMILES: NC(=O)c1cc(c[nH]1)-c1ccncc1Cl

InChI Key: InChIKey=GIVLDIIPJXUCNE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50260930   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
CDK8/Cyclin C (Homo sapiens (Human))	BDBM50260930 (CHEMBL4087403) Show SMILES NC(=O)c1cc(c[nH]1)-c1ccncc1Cl Show InChI InChI=1S/C10H8ClN3O/c11-8-5-13-2-1-7(8)6-3-9(10(12)15)14-4-6/h1-5,14H,(H2,12,15)	PDB KEGG GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Medicinal Chemistry, Roche Innovation Center Shanghai, Bldg 5, 720 Cailun Road, Shanghai 201203, China. Electronic address: cyrus.han@roche.com. Curated by ChEMBL					Assay Description Inhibition of recombinant full length His-tagged human CDK8/Cyclin C expressed in baculovirus expression system using Ulight-GS peptide as substrate ...				Bioorg Med Chem Lett 27: 4488-4492 (2017) Article DOI: 10.1016/j.bmcl.2017.07.080 BindingDB Entry DOI: 10.7270/Q2NP26W9
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