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BDBM50260949 CHEMBL4066087

SMILES: Cn1cc(cc1C(N)=O)-c1ccncc1

InChI Key: InChIKey=STHMQNHNPQEJEN-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50260949   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
CDK8/Cyclin C


(Homo sapiens (Human))		BDBM50260949
PNG
(CHEMBL4066087)
Show SMILES Cn1cc(cc1C(N)=O)-c1ccncc1
Show InChI InChI=1S/C11H11N3O/c1-14-7-9(6-10(14)11(12)15)8-2-4-13-5-3-8/h2-7H,1H3,(H2,12,15)
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KEGG

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 4.95E+3n/an/an/an/an/an/a



Medicinal Chemistry, Roche Innovation Center Shanghai, Bldg 5, 720 Cailun Road, Shanghai 201203, China. Electronic address: cyrus.han@roche.com.

Curated by ChEMBL


Assay Description
Inhibition of recombinant full length His-tagged human CDK8/Cyclin C expressed in baculovirus expression system using Ulight-GS peptide as substrate ...

Bioorg Med Chem Lett 27: 4488-4492 (2017)


Article DOI: 10.1016/j.bmcl.2017.07.080
BindingDB Entry DOI: 10.7270/Q2NP26W9
More data for this
Ligand-Target Pair