BDBM50261839 5,5-dimethyl-2-(6-(6-methylpyridin-3-yl)-2,3-dihydrobenzo[b][1,4]oxazin-4-yl)-5,6-dihydrobenzo[d]thiazol-7(4H)-one::CHEMBL512834

SMILES: Cc1ccc(cn1)-c1ccc2OCCN(c3nc4CC(C)(C)CC(=O)c4s3)c2c1

InChI Key: InChIKey=RQMVABRSLSHVJK-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50261839   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50261839 (5,5-dimethyl-2-(6-(6-methylpyridin-3-yl)-2,3-dihyd...) Show SMILES Cc1ccc(cn1)-c1ccc2OCCN(c3nc4CC(C)(C)CC(=O)c4s3)c2c1 Show InChI InChI=1S/C23H23N3O2S/c1-14-4-5-16(13-24-14)15-6-7-20-18(10-15)26(8-9-28-20)22-25-17-11-23(2,3)12-19(27)21(17)29-22/h4-7,10,13H,8-9,11-12H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
UCB Curated by ChEMBL					Assay Description Inhibition of PI3K delta (unknown origin)				Bioorg Med Chem Lett 18: 4700-4 (2008) Article DOI: 10.1016/j.bmcl.2008.06.104 BindingDB Entry DOI: 10.7270/Q2VM4C2J
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM50261839 (5,5-dimethyl-2-(6-(6-methylpyridin-3-yl)-2,3-dihyd...) Show SMILES Cc1ccc(cn1)-c1ccc2OCCN(c3nc4CC(C)(C)CC(=O)c4s3)c2c1 Show InChI InChI=1S/C23H23N3O2S/c1-14-4-5-16(13-24-14)15-6-7-20-18(10-15)26(8-9-28-20)22-25-17-11-23(2,3)12-19(27)21(17)29-22/h4-7,10,13H,8-9,11-12H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	308	n/a	n/a	n/a	n/a	n/a	n/a
UCB Curated by ChEMBL					Assay Description Inhibition of PI3K beta (unknown origin)				Bioorg Med Chem Lett 18: 4700-4 (2008) Article DOI: 10.1016/j.bmcl.2008.06.104 BindingDB Entry DOI: 10.7270/Q2VM4C2J
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50261839 (5,5-dimethyl-2-(6-(6-methylpyridin-3-yl)-2,3-dihyd...) Show SMILES Cc1ccc(cn1)-c1ccc2OCCN(c3nc4CC(C)(C)CC(=O)c4s3)c2c1 Show InChI InChI=1S/C23H23N3O2S/c1-14-4-5-16(13-24-14)15-6-7-20-18(10-15)26(8-9-28-20)22-25-17-11-23(2,3)12-19(27)21(17)29-22/h4-7,10,13H,8-9,11-12H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	164	n/a	n/a	n/a	n/a	n/a	n/a
UCB Curated by ChEMBL					Assay Description Inhibition of PI3K alpha (unknown origin)				Bioorg Med Chem Lett 18: 4700-4 (2008) Article DOI: 10.1016/j.bmcl.2008.06.104 BindingDB Entry DOI: 10.7270/Q2VM4C2J
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50261839 (5,5-dimethyl-2-(6-(6-methylpyridin-3-yl)-2,3-dihyd...) Show SMILES Cc1ccc(cn1)-c1ccc2OCCN(c3nc4CC(C)(C)CC(=O)c4s3)c2c1 Show InChI InChI=1S/C23H23N3O2S/c1-14-4-5-16(13-24-14)15-6-7-20-18(10-15)26(8-9-28-20)22-25-17-11-23(2,3)12-19(27)21(17)29-22/h4-7,10,13H,8-9,11-12H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
UCB Curated by ChEMBL					Assay Description Inhibition of PI3K gamma (unknown origin)				Bioorg Med Chem Lett 18: 4700-4 (2008) Article DOI: 10.1016/j.bmcl.2008.06.104 BindingDB Entry DOI: 10.7270/Q2VM4C2J
					More data for this Ligand-Target Pair