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SMILES: Cc1cc2cc(NC(NC(=O)c3ccccc3)=N[C@H]3CCCCN(CC(=O)N4CCCC4)C3=O)ccc2o1

InChI Key: InChIKey=GSMFCURCLGIFMR-DEOSSOPVSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50261842   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))		BDBM50261842
PNG
((S)-N-((2-methylbenzofuran-5-ylamino)(2-oxo-1-(2-o...)
Show SMILES Cc1cc2cc(NC(NC(=O)c3ccccc3)=N[C@H]3CCCCN(CC(=O)N4CCCC4)C3=O)ccc2o1 |r,w:7.6|
Show InChI InChI=1S/C29H33N5O4/c1-20-17-22-18-23(12-13-25(22)38-20)30-29(32-27(36)21-9-3-2-4-10-21)31-24-11-5-6-16-34(28(24)37)19-26(35)33-14-7-8-15-33/h2-4,9-10,12-13,17-18,24H,5-8,11,14-16,19H2,1H3,(H2,30,31,32,36)/t24-/m0/s1
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n/an/a 6n/an/an/an/an/an/a



Bristol-Myers Squibb Research and Development

Curated by ChEMBL


Assay Description
Inhibition of human factor 10a

Bioorg Med Chem Lett 18: 4696-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.07.004
BindingDB Entry DOI: 10.7270/Q2QV3MBT
More data for this
Ligand-Target Pair