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SMILES: COc1ccc(NC(NC(=O)c2ccc(OC)cc2)=N[C@H]2CCCCN(CC(=O)N3CCCC3)C2=O)cc1

InChI Key: InChIKey=UZAMPTBIUHMBMY-DEOSSOPVSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50261847   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))		BDBM50261847
PNG
((S)-4-methoxy-N-((4-methoxyphenylamino)(2-oxo-1-(2...)
Show SMILES COc1ccc(NC(NC(=O)c2ccc(OC)cc2)=N[C@H]2CCCCN(CC(=O)N3CCCC3)C2=O)cc1 |r,w:7.6|
Show InChI InChI=1S/C28H35N5O5/c1-37-22-12-8-20(9-13-22)26(35)31-28(29-21-10-14-23(38-2)15-11-21)30-24-7-3-4-18-33(27(24)36)19-25(34)32-16-5-6-17-32/h8-15,24H,3-7,16-19H2,1-2H3,(H2,29,30,31,35)/t24-/m0/s1
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Bristol-Myers Squibb Research and Development

Curated by ChEMBL


Assay Description
Inhibition of human factor 10a

Bioorg Med Chem Lett 18: 4696-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.07.004
BindingDB Entry DOI: 10.7270/Q2QV3MBT
More data for this
Ligand-Target Pair