BDBM50261922 CHEMBL468852::trans-2-fluoro-2-p-tolylcyclopropanamine

SMILES: Cc1ccc(cc1)[C@@]1(F)C[C@@H]1N

InChI Key: InChIKey=JEBMWAUALYWCIW-UWVGGRQHSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50261922   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Amine oxidase (flavin-containing) A (Homo sapiens (Human))	BDBM50261922 (CHEMBL468852 | trans-2-fluoro-2-p-tolylcyclopropan...) Show SMILES Cc1ccc(cc1)[C@@]1(F)C[C@@H]1N |r| Show InChI InChI=1S/C10H12FN/c1-7-2-4-8(5-3-7)10(11)6-9(10)12/h2-5,9H,6,12H2,1H3/t9-,10-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universität Münster Curated by ChEMBL					Assay Description Inhibition of human recombinant MAOA				Bioorg Med Chem 16: 7148-66 (2008) Article DOI: 10.1016/j.bmc.2008.06.048 BindingDB Entry DOI: 10.7270/Q2CN73QW
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50261922 (CHEMBL468852 | trans-2-fluoro-2-p-tolylcyclopropan...) Show SMILES Cc1ccc(cc1)[C@@]1(F)C[C@@H]1N |r| Show InChI InChI=1S/C10H12FN/c1-7-2-4-8(5-3-7)10(11)6-9(10)12/h2-5,9H,6,12H2,1H3/t9-,10-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
School of Pharmacy, University of East Anglia, Norwich Research Park, Norwich NR4 7TJ, United Kingdom. Curated by ChEMBL					Assay Description Inhibition of recombinant human His-tagged LSD1 expressed in Escherichia coli BL21 (DE3) using H3K4me2 peptide as substrate preincubated for 10 mins ...				Bioorg Med Chem Lett 27: 2099-2101 (2017) Article DOI: 10.1016/j.bmcl.2017.03.081 BindingDB Entry DOI: 10.7270/Q2T1562P
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50261922 (CHEMBL468852 | trans-2-fluoro-2-p-tolylcyclopropan...) Show SMILES Cc1ccc(cc1)[C@@]1(F)C[C@@H]1N |r| Show InChI InChI=1S/C10H12FN/c1-7-2-4-8(5-3-7)10(11)6-9(10)12/h2-5,9H,6,12H2,1H3/t9-,10-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
GVK Biosciences Pvt. Ltd. Curated by ChEMBL					Assay Description Inhibition of MAOB				Eur J Med Chem 44: 3584-90 (2009) Article DOI: 10.1016/j.ejmech.2009.02.031 BindingDB Entry DOI: 10.7270/Q2Z60P4F
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50261922 (CHEMBL468852 | trans-2-fluoro-2-p-tolylcyclopropan...) Show SMILES Cc1ccc(cc1)[C@@]1(F)C[C@@H]1N |r| Show InChI InChI=1S/C10H12FN/c1-7-2-4-8(5-3-7)10(11)6-9(10)12/h2-5,9H,6,12H2,1H3/t9-,10-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universität Münster Curated by ChEMBL					Assay Description Inhibition of human recombinant MAOB				Bioorg Med Chem 16: 7148-66 (2008) Article DOI: 10.1016/j.bmc.2008.06.048 BindingDB Entry DOI: 10.7270/Q2CN73QW
					More data for this Ligand-Target Pair