null

SMILES: Cn1nc(C(=O)c2ccccc2NCc2ccc3cn[nH]c3c2)c2ccccc12

InChI Key: InChIKey=HYYGSSGOWQCUKF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50262054   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50262054 ((2-((1H-indazol-6-yl)methylamino)phenyl)(1-methyl-...) Show SMILES Cn1nc(C(=O)c2ccccc2NCc2ccc3cn[nH]c3c2)c2ccccc12 Show InChI InChI=1S/C23H19N5O/c1-28-21-9-5-3-7-18(21)22(27-28)23(29)17-6-2-4-8-19(17)24-13-15-10-11-16-14-25-26-20(16)12-15/h2-12,14,24H,13H2,1H3,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibition of KDR (unknown origin) autophosphorylation by cell based assay				Bioorg Med Chem Lett 18: 4344-7 (2008) Article DOI: 10.1016/j.bmcl.2008.06.083 BindingDB Entry DOI: 10.7270/Q2542NF0
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50262054 ((2-((1H-indazol-6-yl)methylamino)phenyl)(1-methyl-...) Show SMILES Cn1nc(C(=O)c2ccccc2NCc2ccc3cn[nH]c3c2)c2ccccc12 Show InChI InChI=1S/C23H19N5O/c1-28-21-9-5-3-7-18(21)22(27-28)23(29)17-6-2-4-8-19(17)24-13-15-10-11-16-14-25-26-20(16)12-15/h2-12,14,24H,13H2,1H3,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Inc Curated by ChEMBL					Assay Description Inhibition of KDR (unknown origin) by HTRF assay				Bioorg Med Chem Lett 18: 4344-7 (2008) Article DOI: 10.1016/j.bmcl.2008.06.083 BindingDB Entry DOI: 10.7270/Q2542NF0
					More data for this Ligand-Target Pair