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SMILES: Cc1nc(C)c(s1)C(=O)NC(Nc1cccc(C)c1)=N[C@H]1CCCCN(CC(=O)N2CCCC2)C1=O

InChI Key: InChIKey=INQANWBOIDMWHI-NRFANRHFSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50262346   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))		BDBM50262346
PNG
((S)-N-((m-toluidino)(2-oxo-1-(2-oxo-2-(pyrrolidin-...)
Show SMILES Cc1nc(C)c(s1)C(=O)NC(Nc1cccc(C)c1)=N[C@H]1CCCCN(CC(=O)N2CCCC2)C1=O |r,w:10.11|
Show InChI InChI=1S/C26H34N6O3S/c1-17-9-8-10-20(15-17)28-26(30-24(34)23-18(2)27-19(3)36-23)29-21-11-4-5-14-32(25(21)35)16-22(33)31-12-6-7-13-31/h8-10,15,21H,4-7,11-14,16H2,1-3H3,(H2,28,29,30,34)/t21-/m0/s1
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Bristol-Myers Squibb Research and Development

Curated by ChEMBL


Assay Description
Inhibition of human factor 10a

Bioorg Med Chem Lett 18: 4696-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.07.004
BindingDB Entry DOI: 10.7270/Q2QV3MBT
More data for this
Ligand-Target Pair