BDBM50262348 (S)-2,4-dimethyl-N-((2-methylbenzofuran-5-ylamino)(2-oxo-1-(2-oxo-2-(pyrrolidin-1-yl)ethyl)azepan-3-ylamino)methylene)thiazole-5-carboxamide::CHEMBL463719

SMILES: Cc1cc2cc(NC(NC(=O)c3sc(C)nc3C)=N[C@H]3CCCCN(CC(=O)N4CCCC4)C3=O)ccc2o1

InChI Key: InChIKey=UNCBWZKLGFAFHA-QFIPXVFZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50262348   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50262348 ((S)-2,4-dimethyl-N-((2-methylbenzofuran-5-ylamino)...) Show SMILES Cc1cc2cc(NC(NC(=O)c3sc(C)nc3C)=N[C@H]3CCCCN(CC(=O)N4CCCC4)C3=O)ccc2o1 |r,w:7.6| Show InChI InChI=1S/C28H34N6O4S/c1-17-14-20-15-21(9-10-23(20)38-17)30-28(32-26(36)25-18(2)29-19(3)39-25)31-22-8-4-5-13-34(27(22)37)16-24(35)33-11-6-7-12-33/h9-10,14-15,22H,4-8,11-13,16H2,1-3H3,(H2,30,31,32,36)/t22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human factor 10a				Bioorg Med Chem Lett 18: 4696-9 (2008) Article DOI: 10.1016/j.bmcl.2008.07.004 BindingDB Entry DOI: 10.7270/Q2QV3MBT
					More data for this Ligand-Target Pair