BDBM50262972 (4-(naphthalen-2-yl)piperazin-1-yl)(2-p-tolyl-1-(3-(2,2,2-trifluoroethoxy)phenyl)-1H-imidazol-4-yl)methanone::CHEMBL448597

SMILES: Cc1ccc(cc1)-c1nc(cn1-c1cccc(OCC(F)(F)F)c1)C(=O)N1CCN(CC1)c1ccc2ccccc2c1

InChI Key: InChIKey=QWDRHJLDLQTEPH-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50262972   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50262972 ((4-(naphthalen-2-yl)piperazin-1-yl)(2-p-tolyl-1-(3...) Show SMILES Cc1ccc(cc1)-c1nc(cn1-c1cccc(OCC(F)(F)F)c1)C(=O)N1CCN(CC1)c1ccc2ccccc2c1 Show InChI InChI=1S/C33H29F3N4O2/c1-23-9-11-25(12-10-23)31-37-30(21-40(31)28-7-4-8-29(20-28)42-22-33(34,35)36)32(41)39-17-15-38(16-18-39)27-14-13-24-5-2-3-6-26(24)19-27/h2-14,19-21H,15-18,22H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human CCK1 receptor				Bioorg Med Chem Lett 18: 4393-6 (2008) Article DOI: 10.1016/j.bmcl.2008.06.057 BindingDB Entry DOI: 10.7270/Q2HH6JW0
					More data for this Ligand-Target Pair
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50262972 ((4-(naphthalen-2-yl)piperazin-1-yl)(2-p-tolyl-1-(3...) Show SMILES Cc1ccc(cc1)-c1nc(cn1-c1cccc(OCC(F)(F)F)c1)C(=O)N1CCN(CC1)c1ccc2ccccc2c1 Show InChI InChI=1S/C33H29F3N4O2/c1-23-9-11-25(12-10-23)31-37-30(21-40(31)28-7-4-8-29(20-28)42-22-33(34,35)36)32(41)39-17-15-38(16-18-39)27-14-13-24-5-2-3-6-26(24)19-27/h2-14,19-21H,15-18,22H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.35E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Agonist activity against human CCK1 receptor				Bioorg Med Chem Lett 18: 4393-6 (2008) Article DOI: 10.1016/j.bmcl.2008.06.057 BindingDB Entry DOI: 10.7270/Q2HH6JW0
					More data for this Ligand-Target Pair