BDBM50263675 4-fluoro-N-(2-oxo-2-(phenyl(o-tolyl)methylamino)ethyl)benzamide::CHEMBL476775

SMILES: Cc1ccccc1C(NC(=O)CNC(=O)c1ccc(F)cc1)c1ccccc1

InChI Key: InChIKey=PFYPNHSILULSMN-UHFFFAOYSA-N

Data: 3 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50263675   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycine transporter 2 (Homo sapiens (Human))	BDBM50263675 (4-fluoro-N-(2-oxo-2-(phenyl(o-tolyl)methylamino)et...) Show SMILES Cc1ccccc1C(NC(=O)CNC(=O)c1ccc(F)cc1)c1ccccc1 Show InChI InChI=1S/C23H21FN2O2/c1-16-7-5-6-10-20(16)22(17-8-3-2-4-9-17)26-21(27)15-25-23(28)18-11-13-19(24)14-12-18/h2-14,22H,15H2,1H3,(H,25,28)(H,26,27)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Inhibition of [3H]glycine uptake at human glycine transporter 2 transfected in Flp-inTM-CHO				Bioorg Med Chem Lett 18: 5533-6 (2008) Article DOI: 10.1016/j.bmcl.2008.09.005 BindingDB Entry DOI: 10.7270/Q2BR8S19
					More data for this Ligand-Target Pair
Glycine transporter 1 (Homo sapiens (Human))	BDBM50263675 (4-fluoro-N-(2-oxo-2-(phenyl(o-tolyl)methylamino)et...) Show SMILES Cc1ccccc1C(NC(=O)CNC(=O)c1ccc(F)cc1)c1ccccc1 Show InChI InChI=1S/C23H21FN2O2/c1-16-7-5-6-10-20(16)22(17-8-3-2-4-9-17)26-21(27)15-25-23(28)18-11-13-19(24)14-12-18/h2-14,22H,15H2,1H3,(H,25,28)(H,26,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	4.05E+3	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Inhibition of [3H]glycine uptake at human glycine transporter 1 transfected in Flp-inTM-CHO				Bioorg Med Chem Lett 18: 5533-6 (2008) Article DOI: 10.1016/j.bmcl.2008.09.005 BindingDB Entry DOI: 10.7270/Q2BR8S19
					More data for this Ligand-Target Pair
Cytochrome P450 2C9 (Homo sapiens (Human))	BDBM50263675 (4-fluoro-N-(2-oxo-2-(phenyl(o-tolyl)methylamino)et...) Show SMILES Cc1ccccc1C(NC(=O)CNC(=O)c1ccc(F)cc1)c1ccccc1 Show InChI InChI=1S/C23H21FN2O2/c1-16-7-5-6-10-20(16)22(17-8-3-2-4-9-17)26-21(27)15-25-23(28)18-11-13-19(24)14-12-18/h2-14,22H,15H2,1H3,(H,25,28)(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Inhibition of CYP2C9				Bioorg Med Chem Lett 18: 5533-6 (2008) Article DOI: 10.1016/j.bmcl.2008.09.005 BindingDB Entry DOI: 10.7270/Q2BR8S19
					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50263675 (4-fluoro-N-(2-oxo-2-(phenyl(o-tolyl)methylamino)et...) Show SMILES Cc1ccccc1C(NC(=O)CNC(=O)c1ccc(F)cc1)c1ccccc1 Show InChI InChI=1S/C23H21FN2O2/c1-16-7-5-6-10-20(16)22(17-8-3-2-4-9-17)26-21(27)15-25-23(28)18-11-13-19(24)14-12-18/h2-14,22H,15H2,1H3,(H,25,28)(H,26,27)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Inhibition of CYP2D6				Bioorg Med Chem Lett 18: 5533-6 (2008) Article DOI: 10.1016/j.bmcl.2008.09.005 BindingDB Entry DOI: 10.7270/Q2BR8S19
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50263675 (4-fluoro-N-(2-oxo-2-(phenyl(o-tolyl)methylamino)et...) Show SMILES Cc1ccccc1C(NC(=O)CNC(=O)c1ccc(F)cc1)c1ccccc1 Show InChI InChI=1S/C23H21FN2O2/c1-16-7-5-6-10-20(16)22(17-8-3-2-4-9-17)26-21(27)15-25-23(28)18-11-13-19(24)14-12-18/h2-14,22H,15H2,1H3,(H,25,28)(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Inhibition of CYP3A4				Bioorg Med Chem Lett 18: 5533-6 (2008) Article DOI: 10.1016/j.bmcl.2008.09.005 BindingDB Entry DOI: 10.7270/Q2BR8S19
					More data for this Ligand-Target Pair