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SMILES: O=C(NCc1cccs1)c1ccnc2c(SSc3cccc4c(ccnc34)C(=O)NCc3cccs3)cccc12

InChI Key: InChIKey=ANEKDCBJYOLYPY-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50264518   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
26S proteasome non-ATPase regulatory subunit 14


(Homo sapiens (Human))		BDBM50264518
PNG
(CHEMBL4087722)
Show SMILES O=C(NCc1cccs1)c1ccnc2c(SSc3cccc4c(ccnc34)C(=O)NCc3cccs3)cccc12
Show InChI InChI=1S/C30H22N4O2S4/c35-29(33-17-19-5-3-15-37-19)23-11-13-31-27-21(23)7-1-9-25(27)39-40-26-10-2-8-22-24(12-14-32-28(22)26)30(36)34-18-20-6-4-16-38-20/h1-16H,17-18H2,(H,33,35)(H,34,36)
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antibodypedia
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UniChem

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Article
PubMed
n/an/a 1.00E+3n/an/an/an/an/an/a



University of California San Diego

Curated by ChEMBL


Assay Description
Inhibition of 26S proteasome regulatory subunit RPN11 deubiquitinating activity in human erythrocytes using Ub4-pepOG protein substrate preincubated ...

J Med Chem 60: 1343-1361 (2017)


Article DOI: 10.1021/acs.jmedchem.6b01379
BindingDB Entry DOI: 10.7270/Q22F7QX5
More data for this
Ligand-Target Pair