BDBM50264555 CHEMBL4093484

SMILES: OC(=O)c1cnc2c(SSc3cccc4cc(cnc34)C(O)=O)cccc2c1

InChI Key: InChIKey=RCYABFBTLSDRIP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50264555   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
26S Proteasome regulatory subunit Rpn11 (Rpn11) (Homo sapiens (Human))	BDBM50264555 (CHEMBL4093484) Show SMILES OC(=O)c1cnc2c(SSc3cccc4cc(cnc34)C(O)=O)cccc2c1 Show InChI InChI=1S/C20H12N2O4S2/c23-19(24)13-7-11-3-1-5-15(17(11)21-9-13)27-28-16-6-2-4-12-8-14(20(25)26)10-22-18(12)16/h1-10H,(H,23,24)(H,25,26)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Diego Curated by ChEMBL					Assay Description Inhibition of 26S proteasome regulatory subunit RPN11 deubiquitinating activity in human erythrocytes using Ub4-pepOG protein substrate preincubated ...				J Med Chem 60: 1343-1361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01379 BindingDB Entry DOI: 10.7270/Q22F7QX5
					More data for this Ligand-Target Pair