BDBM50265171 4-(4-((2,4,6-trioxotetrahydropyrimidin-5(6H)-ylidene)methyl)benzyloxy)benzonitrile::CHEMBL522727

SMILES: O=[#6]-1-[#7]-[#6](=O)\[#6](=[#6]\c2ccc(-[#8]-[#6]-[#6]-[#8]-c3ccc(cc3)C#N)cc2)-[#6](=O)-[#7]-1

InChI Key: InChIKey=MNCKLTMXSGWKTH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50265171   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor gamma (Mus musculus)	BDBM50265171 (4-(4-((2,4,6-trioxotetrahydropyrimidin-5(6H)-ylide...) Show SMILES O=[#6]-1-[#7]-[#6](=O)\[#6](=[#6]\c2ccc(-[#8]-[#6]-[#6]-[#8]-c3ccc(cc3)C#N)cc2)-[#6](=O)-[#7]-1 Show InChI InChI=1S/C20H15N3O5/c21-12-14-3-7-16(8-4-14)28-10-9-27-15-5-1-13(2-6-15)11-17-18(24)22-20(26)23-19(17)25/h1-8,11H,9-10H2,(H2,22,23,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Pharmaceutical Education and Research Curated by ChEMBL					Assay Description Displacement of [3H]rosiglitazone from mouse PPARgamma receptor by scintillation proximation assay				Bioorg Med Chem Lett 18: 4959-62 (2008) Article DOI: 10.1016/j.bmcl.2008.08.028 BindingDB Entry DOI: 10.7270/Q2X066VZ
					More data for this Ligand-Target Pair