BDBM50265362 2-(6-(1-(3-aminopropyl)-3-methyl-1H-pyrazol-4-yl)-2H-benzo[b][1,4]oxazin-4(3H)-yl)-6,6-dimethyl-6,7-dihydrothiazolo[5,4-c]pyridin-4(5H)-one::CHEMBL526463

SMILES: Cc1nn(CCCN)cc1-c1ccc2OCCN(c3nc4CC(C)(C)NC(=O)c4s3)c2c1

InChI Key: InChIKey=BORTYQMHWOIPRH-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50265362   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50265362 (2-(6-(1-(3-aminopropyl)-3-methyl-1H-pyrazol-4-yl)-...) Show SMILES Cc1nn(CCCN)cc1-c1ccc2OCCN(c3nc4CC(C)(C)NC(=O)c4s3)c2c1 Show InChI InChI=1S/C23H28N6O2S/c1-14-16(13-28(27-14)8-4-7-24)15-5-6-19-18(11-15)29(9-10-31-19)22-25-17-12-23(2,3)26-21(30)20(17)32-22/h5-6,11,13H,4,7-10,12,24H2,1-3H3,(H,26,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
UCB Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma (unknown origin)				Bioorg Med Chem Lett 18: 5299-302 (2008) Article DOI: 10.1016/j.bmcl.2008.08.042 BindingDB Entry DOI: 10.7270/Q2WS8T3X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50265362 (2-(6-(1-(3-aminopropyl)-3-methyl-1H-pyrazol-4-yl)-...) Show SMILES Cc1nn(CCCN)cc1-c1ccc2OCCN(c3nc4CC(C)(C)NC(=O)c4s3)c2c1 Show InChI InChI=1S/C23H28N6O2S/c1-14-16(13-28(27-14)8-4-7-24)15-5-6-19-18(11-15)29(9-10-31-19)22-25-17-12-23(2,3)26-21(30)20(17)32-22/h5-6,11,13H,4,7-10,12,24H2,1-3H3,(H,26,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
UCB Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta (unknown origin)				Bioorg Med Chem Lett 18: 5299-302 (2008) Article DOI: 10.1016/j.bmcl.2008.08.042 BindingDB Entry DOI: 10.7270/Q2WS8T3X
					More data for this Ligand-Target Pair