BDBM50266694 CHEMBL4069307

SMILES: CC[C@H](C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)[C@@H](C)CC)C(=O)N[C@@H](C)C(N)=O

InChI Key: InChIKey=DQEMNHIUGLTOFP-OCMQTXBHSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50266694   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucagon receptor (Homo sapiens (Human))	BDBM50266694 (CHEMBL4069307) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)[C@@H](C)CC)C(=O)N[C@@H](C)C(N)=O |r| Show InChI InChI=1S/C175H273N55O59S/c1-14-83(7)136(170(286)198-85(9)140(185)256)227-162(278)112(65-128(184)244)214-156(272)111(64-127(183)243)215-166(282)119(77-234)223-168(284)120(78-235)224-169(285)122-41-30-55-230(122)131(247)73-194-129(245)71-195-144(260)110(63-126(182)242)213-148(264)97(38-25-27-52-177)202-153(269)105(57-81(3)4)209-155(271)109(61-91-69-193-95-36-23-22-35-93(91)95)212-151(267)103(45-49-132(248)249)208-171(287)137(84(8)15-2)228-160(276)107(59-89-31-18-16-19-32-89)211-158(274)113(66-133(250)251)216-150(266)101(43-47-124(180)240)200-141(257)86(10)199-145(261)98(39-28-53-191-174(186)187)201-147(263)99(40-29-54-192-175(188)189)204-165(281)118(76-233)222-159(275)115(68-135(254)255)217-152(268)104(50-56-290-13)207-149(265)102(44-48-125(181)241)206-146(262)96(37-24-26-51-176)203-164(280)117(75-232)221-154(270)106(58-82(5)6)210-157(273)114(67-134(252)253)218-167(283)121(79-236)225-173(289)139(88(12)238)229-161(277)108(60-90-33-20-17-21-34-90)219-172(288)138(87(11)237)226-130(246)72-196-143(259)100(42-46-123(179)239)205-163(279)116(74-231)220-142(258)94(178)62-92-70-190-80-197-92/h16-23,31-36,69-70,80-88,94,96-122,136-139,193,231-238H,14-15,24-30,37-68,71-79,176-178H2,1-13H3,(H2,179,239)(H2,180,240)(H2,181,241)(H2,182,242)(H2,183,243)(H2,184,244)(H2,185,256)(H,190,197)(H,194,245)(H,195,260)(H,196,259)(H,198,286)(H,199,261)(H,200,257)(H,201,263)(H,202,269)(H,203,280)(H,204,281)(H,205,279)(H,206,262)(H,207,265)(H,208,287)(H,209,271)(H,210,273)(H,211,274)(H,212,267)(H,213,264)(H,214,272)(H,215,282)(H,216,266)(H,217,268)(H,218,283)(H,219,288)(H,220,258)(H,221,270)(H,222,275)(H,223,284)(H,224,285)(H,225,289)(H,226,246)(H,227,278)(H,228,276)(H,229,277)(H,248,249)(H,250,251)(H,252,253)(H,254,255)(H4,186,187,191)(H4,188,189,192)/t83-,84-,85-,86-,87+,88+,94-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,136-,137-,138-,139-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	16	n/a	n/a	n/a	n/a
Sanofi-Aventis Deutschland GmbH Curated by ChEMBL					Assay Description Agonist activity at human glucagon receptor expressed in HEK293 cells assessed as cAMP accumulation after 30 mins by HTRF assay				J Med Chem 60: 4293-4303 (2017) Article DOI: 10.1021/acs.jmedchem.7b00174 BindingDB Entry DOI: 10.7270/Q27S7R7M
					More data for this Ligand-Target Pair
Glucagon-like peptide 1 receptor (Homo sapiens (Human))	BDBM50266694 (CHEMBL4069307) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)[C@@H](C)CC)C(=O)N[C@@H](C)C(N)=O |r| Show InChI InChI=1S/C175H273N55O59S/c1-14-83(7)136(170(286)198-85(9)140(185)256)227-162(278)112(65-128(184)244)214-156(272)111(64-127(183)243)215-166(282)119(77-234)223-168(284)120(78-235)224-169(285)122-41-30-55-230(122)131(247)73-194-129(245)71-195-144(260)110(63-126(182)242)213-148(264)97(38-25-27-52-177)202-153(269)105(57-81(3)4)209-155(271)109(61-91-69-193-95-36-23-22-35-93(91)95)212-151(267)103(45-49-132(248)249)208-171(287)137(84(8)15-2)228-160(276)107(59-89-31-18-16-19-32-89)211-158(274)113(66-133(250)251)216-150(266)101(43-47-124(180)240)200-141(257)86(10)199-145(261)98(39-28-53-191-174(186)187)201-147(263)99(40-29-54-192-175(188)189)204-165(281)118(76-233)222-159(275)115(68-135(254)255)217-152(268)104(50-56-290-13)207-149(265)102(44-48-125(181)241)206-146(262)96(37-24-26-51-176)203-164(280)117(75-232)221-154(270)106(58-82(5)6)210-157(273)114(67-134(252)253)218-167(283)121(79-236)225-173(289)139(88(12)238)229-161(277)108(60-90-33-20-17-21-34-90)219-172(288)138(87(11)237)226-130(246)72-196-143(259)100(42-46-123(179)239)205-163(279)116(74-231)220-142(258)94(178)62-92-70-190-80-197-92/h16-23,31-36,69-70,80-88,94,96-122,136-139,193,231-238H,14-15,24-30,37-68,71-79,176-178H2,1-13H3,(H2,179,239)(H2,180,240)(H2,181,241)(H2,182,242)(H2,183,243)(H2,184,244)(H2,185,256)(H,190,197)(H,194,245)(H,195,260)(H,196,259)(H,198,286)(H,199,261)(H,200,257)(H,201,263)(H,202,269)(H,203,280)(H,204,281)(H,205,279)(H,206,262)(H,207,265)(H,208,287)(H,209,271)(H,210,273)(H,211,274)(H,212,267)(H,213,264)(H,214,272)(H,215,282)(H,216,266)(H,217,268)(H,218,283)(H,219,288)(H,220,258)(H,221,270)(H,222,275)(H,223,284)(H,224,285)(H,225,289)(H,226,246)(H,227,278)(H,228,276)(H,229,277)(H,248,249)(H,250,251)(H,252,253)(H,254,255)(H4,186,187,191)(H4,188,189,192)/t83-,84-,85-,86-,87+,88+,94-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,136-,137-,138-,139-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	17	n/a	n/a	n/a	n/a
Sanofi-Aventis Deutschland GmbH Curated by ChEMBL					Assay Description Agonist activity at human GLP-1 receptor expressed in HEK293 cells assessed as cAMP accumulation after 30 mins by HTRF assay				J Med Chem 60: 4293-4303 (2017) Article DOI: 10.1021/acs.jmedchem.7b00174 BindingDB Entry DOI: 10.7270/Q27S7R7M
					More data for this Ligand-Target Pair