BDBM50266700 CHEMBL4079721

SMILES: CC(=O)N[C@@H](Cc1csc2ccccc12)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@@H](Cc1csc2ccccc12)C(N)=O

InChI Key: InChIKey=VVHOGOJXZCVGIT-IHZBLBIESA-N

Data: 4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50266700   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Mus musculus)	BDBM50266700 (CHEMBL4079721) Show SMILES CC(=O)N[C@@H](Cc1csc2ccccc12)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@@H](Cc1csc2ccccc12)C(N)=O |r| Show InChI InChI=1S/C39H43IN8O5S2/c1-22(49)45-32(19-25-21-55-34-11-5-3-8-28(25)34)38(53)46-29(9-6-16-44-39(42)43)36(51)48-31(17-23-12-14-26(40)15-13-23)37(52)47-30(35(41)50)18-24-20-54-33-10-4-2-7-27(24)33/h2-5,7-8,10-15,20-21,29-32H,6,9,16-19H2,1H3,(H2,41,50)(H,45,49)(H,46,53)(H,47,52)(H,48,51)(H4,42,43,44)/t29-,30-,31+,32-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at mouse MC4R expressed in HEK293 cells assessed as induction of cAMP accumulation after 2 hrs by alpha screen assay				J Med Chem 60: 4342-4357 (2017) Article DOI: 10.1021/acs.jmedchem.7b00301 BindingDB Entry DOI: 10.7270/Q24170J1
					More data for this Ligand-Target Pair
Melanocortin receptor 3 (Mus musculus)	BDBM50266700 (CHEMBL4079721) Show SMILES CC(=O)N[C@@H](Cc1csc2ccccc12)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@@H](Cc1csc2ccccc12)C(N)=O |r| Show InChI InChI=1S/C39H43IN8O5S2/c1-22(49)45-32(19-25-21-55-34-11-5-3-8-28(25)34)38(53)46-29(9-6-16-44-39(42)43)36(51)48-31(17-23-12-14-26(40)15-13-23)37(52)47-30(35(41)50)18-24-20-54-33-10-4-2-7-27(24)33/h2-5,7-8,10-15,20-21,29-32H,6,9,16-19H2,1H3,(H2,41,50)(H,45,49)(H,46,53)(H,47,52)(H,48,51)(H4,42,43,44)/t29-,30-,31+,32-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at mouse MC3R expressed in HEK293 cells assessed as induction of cAMP accumulation after 2 hrs by alpha screen assay				J Med Chem 60: 4342-4357 (2017) Article DOI: 10.1021/acs.jmedchem.7b00301 BindingDB Entry DOI: 10.7270/Q24170J1
					More data for this Ligand-Target Pair
Melanocortin receptor 5 (Mus musculus (Mouse))	BDBM50266700 (CHEMBL4079721) Show SMILES CC(=O)N[C@@H](Cc1csc2ccccc12)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@@H](Cc1csc2ccccc12)C(N)=O |r| Show InChI InChI=1S/C39H43IN8O5S2/c1-22(49)45-32(19-25-21-55-34-11-5-3-8-28(25)34)38(53)46-29(9-6-16-44-39(42)43)36(51)48-31(17-23-12-14-26(40)15-13-23)37(52)47-30(35(41)50)18-24-20-54-33-10-4-2-7-27(24)33/h2-5,7-8,10-15,20-21,29-32H,6,9,16-19H2,1H3,(H2,41,50)(H,45,49)(H,46,53)(H,47,52)(H,48,51)(H4,42,43,44)/t29-,30-,31+,32-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at mouse MC5R expressed in HEK293 cells assessed as induction of cAMP accumulation after 2 hrs by alpha screen assay				J Med Chem 60: 4342-4357 (2017) Article DOI: 10.1021/acs.jmedchem.7b00301 BindingDB Entry DOI: 10.7270/Q24170J1
					More data for this Ligand-Target Pair
Melanocortin receptor 1 (Mus musculus)	BDBM50266700 (CHEMBL4079721) Show SMILES CC(=O)N[C@@H](Cc1csc2ccccc12)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@@H](Cc1csc2ccccc12)C(N)=O |r| Show InChI InChI=1S/C39H43IN8O5S2/c1-22(49)45-32(19-25-21-55-34-11-5-3-8-28(25)34)38(53)46-29(9-6-16-44-39(42)43)36(51)48-31(17-23-12-14-26(40)15-13-23)37(52)47-30(35(41)50)18-24-20-54-33-10-4-2-7-27(24)33/h2-5,7-8,10-15,20-21,29-32H,6,9,16-19H2,1H3,(H2,41,50)(H,45,49)(H,46,53)(H,47,52)(H,48,51)(H4,42,43,44)/t29-,30-,31+,32-/m0/s1	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at mouse MC1R expressed in HEK293 cells assessed as induction of cAMP accumulation after 2 hrs by alpha screen assay				J Med Chem 60: 4342-4357 (2017) Article DOI: 10.1021/acs.jmedchem.7b00301 BindingDB Entry DOI: 10.7270/Q24170J1
					More data for this Ligand-Target Pair