Found 4 hits for monomerid = 50266756 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Melanocortin receptor 3
(Mus musculus) | BDBM50266756
![PNG](/data/jpeg/tenK5026/BindingDB_50266756.png) (CHEMBL4068777)Show SMILES CC(=O)N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@H](Cc1ccc2ccccc2c1)C(N)=O |r| Show InChI InChI=1S/C43H47IN8O5/c1-26(53)49-37(25-29-13-17-31-8-3-5-10-33(31)22-29)41(56)50-35(11-6-20-48-43(46)47)40(55)52-38(23-27-14-18-34(44)19-15-27)42(57)51-36(39(45)54)24-28-12-16-30-7-2-4-9-32(30)21-28/h2-5,7-10,12-19,21-22,35-38H,6,11,20,23-25H2,1H3,(H2,45,54)(H,49,53)(H,50,56)(H,51,57)(H,52,55)(H4,46,47,48)/t35-,36+,37+,38+/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| | 320 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50266756
![PNG](/data/jpeg/tenK5026/BindingDB_50266756.png) (CHEMBL4068777)Show SMILES CC(=O)N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@H](Cc1ccc2ccccc2c1)C(N)=O |r| Show InChI InChI=1S/C43H47IN8O5/c1-26(53)49-37(25-29-13-17-31-8-3-5-10-33(31)22-29)41(56)50-35(11-6-20-48-43(46)47)40(55)52-38(23-27-14-18-34(44)19-15-27)42(57)51-36(39(45)54)24-28-12-16-30-7-2-4-9-32(30)21-28/h2-5,7-10,12-19,21-22,35-38H,6,11,20,23-25H2,1H3,(H2,45,54)(H,49,53)(H,50,56)(H,51,57)(H,52,55)(H4,46,47,48)/t35-,36+,37+,38+/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| | 790 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50266756
![PNG](/data/jpeg/tenK5026/BindingDB_50266756.png) (CHEMBL4068777)Show SMILES CC(=O)N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@H](Cc1ccc2ccccc2c1)C(N)=O |r| Show InChI InChI=1S/C43H47IN8O5/c1-26(53)49-37(25-29-13-17-31-8-3-5-10-33(31)22-29)41(56)50-35(11-6-20-48-43(46)47)40(55)52-38(23-27-14-18-34(44)19-15-27)42(57)51-36(39(45)54)24-28-12-16-30-7-2-4-9-32(30)21-28/h2-5,7-10,12-19,21-22,35-38H,6,11,20,23-25H2,1H3,(H2,45,54)(H,49,53)(H,50,56)(H,51,57)(H,52,55)(H4,46,47,48)/t35-,36+,37+,38+/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a |
University of Minnesota
Curated by ChEMBL
| Assay Description Agonist activity at mouse MC1R expressed in HEK293 cells assessed as induction of cAMP accumulation after 2 hrs by alpha screen assay |
J Med Chem 60: 4342-4357 (2017)
Article DOI: 10.1021/acs.jmedchem.7b00301 BindingDB Entry DOI: 10.7270/Q24170J1 |
More data for this Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50266756
![PNG](/data/jpeg/tenK5026/BindingDB_50266756.png) (CHEMBL4068777)Show SMILES CC(=O)N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@H](Cc1ccc2ccccc2c1)C(N)=O |r| Show InChI InChI=1S/C43H47IN8O5/c1-26(53)49-37(25-29-13-17-31-8-3-5-10-33(31)22-29)41(56)50-35(11-6-20-48-43(46)47)40(55)52-38(23-27-14-18-34(44)19-15-27)42(57)51-36(39(45)54)24-28-12-16-30-7-2-4-9-32(30)21-28/h2-5,7-10,12-19,21-22,35-38H,6,11,20,23-25H2,1H3,(H2,45,54)(H,49,53)(H,50,56)(H,51,57)(H,52,55)(H4,46,47,48)/t35-,36+,37+,38+/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |