BDBM50266769 CHEMBL476794::ethyl 2-(naphthalen-1-ylamino)-5-(4-nitrobenzylidene)-4-oxo-4,5-dihydrothiophene-3-carboxylate
SMILES: CCOC(=O)C1C(=O)C(SC1=Nc1cccc2ccccc12)=Cc1ccc(cc1)[N+]([O-])=O
InChI Key: InChIKey=RAKFWJWJWKXVEG-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Nicotinamide adenine dinucleotide synthetase (NADs) (Bacillus anthracis) | BDBM50266769 (CHEMBL476794 | ethyl 2-(naphthalen-1-ylamino)-5-(4...) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 8.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alabama at Birmingham Curated by ChEMBL | Assay Description Inhibition of Bacillus anthracis NAD synthetase | Bioorg Med Chem Lett 19: 2001-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.034 BindingDB Entry DOI: 10.7270/Q2ST7PQC | |||||||||||
More data for this Ligand-Target Pair |