BDBM50266801 CHEMBL475967::N-(4-fluorophenyl)-2-(3-(2-(5-nitro-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)vinyl)-1H-indol-1-yl)acetamide
SMILES: [O-][N+](=O)c1c(C=Cc2cn(CC(=O)Nc3ccc(F)cc3)c3ccccc23)[nH]c(=O)[nH]c1=O
InChI Key: InChIKey=PSDSNDLFWBHJAH-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Nicotinamide adenine dinucleotide synthetase (NADs) (Bacillus anthracis) | BDBM50266801![]() (CHEMBL475967 | N-(4-fluorophenyl)-2-(3-(2-(5-nitro...) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.54E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alabama at Birmingham Curated by ChEMBL | Assay Description Inhibition of Bacillus anthracis NAD synthetase | Bioorg Med Chem Lett 19: 2001-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.034 BindingDB Entry DOI: 10.7270/Q2ST7PQC | |||||||||||
More data for this Ligand-Target Pair |