BDBM50267149 CHEMBL4071607

SMILES: Cl.[H][C@@]12CCc3nnc(-c4csc(C)n4)n3[C@]1([H])CCN(C2)C(=O)C[C@H](N)Cc1cc(F)c(F)cc1F

InChI Key: InChIKey=NGPBEWBDWSTZRZ-RFXIGBPJSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50267149   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50267149 (CHEMBL4071607) Show SMILES Cl.[H][C@@]12CCc3nnc(-c4csc(C)n4)n3[C@]1([H])CCN(C2)C(=O)C[C@H](N)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C23H25F3N6OS.ClH/c1-12-28-19(11-34-12)23-30-29-21-3-2-13-10-31(5-4-20(13)32(21)23)22(33)8-15(27)6-14-7-17(25)18(26)9-16(14)24;/h7,9,11,13,15,20H,2-6,8,10,27H2,1H3;1H/t13-,15+,20+;/m0./s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
University Park Nottingham Curated by ChEMBL					Assay Description Inhibition of recombinant human DPP-4 expressed in HEK293 cells using H-Gly-Pro-AMC as substrate measured over 15 mins by fluorescence analysis				J Med Chem 60: 1534-1554 (2017) Article DOI: 10.1021/acs.jmedchem.6b01801 BindingDB Entry DOI: 10.7270/Q2251MPR
					More data for this Ligand-Target Pair