BDBM50267178 CHEMBL4093298

SMILES: Cl.[H][C@@]12CCc3nnc(-c4cccc(OCC)n4)n3[C@]1([H])CCN(C2)C(=O)C[C@H](N)Cc1cc(F)c(F)cc1F

InChI Key: InChIKey=CITBPMUCAXWFAY-UTNOBSBTSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50267178   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50267178 (CHEMBL4093298) Show SMILES Cl.[H][C@@]12CCc3nnc(-c4cccc(OCC)n4)n3[C@]1([H])CCN(C2)C(=O)C[C@H](N)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C26H29F3N6O2.ClH/c1-2-37-24-5-3-4-21(31-24)26-33-32-23-7-6-15-14-34(9-8-22(15)35(23)26)25(36)12-17(30)10-16-11-19(28)20(29)13-18(16)27;/h3-5,11,13,15,17,22H,2,6-10,12,14,30H2,1H3;1H/t15-,17+,22+;/m0./s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	139	n/a	n/a	n/a	n/a	n/a	n/a
University Park Nottingham Curated by ChEMBL					Assay Description Inhibition of recombinant human DPP-4 expressed in HEK293 cells using H-Gly-Pro-AMC as substrate measured over 15 mins by fluorescence analysis				J Med Chem 60: 1534-1554 (2017) Article DOI: 10.1021/acs.jmedchem.6b01801 BindingDB Entry DOI: 10.7270/Q2251MPR
					More data for this Ligand-Target Pair