BDBM50267211 CHEMBL4068843

SMILES: O=C(NCC[C@@H]1C[C@H]1CN1CCc2ccc(cc2C1)C#N)c1cc2cccnc2[nH]1

InChI Key: InChIKey=ZXMQIPPBQZMPBZ-NQIIRXRSSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50267211   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50267211 (CHEMBL4068843) Show SMILES O=C(NCC[C@@H]1C[C@H]1CN1CCc2ccc(cc2C1)C#N)c1cc2cccnc2[nH]1 |r| Show InChI InChI=1S/C24H25N5O/c25-13-16-3-4-17-6-9-29(14-20(17)10-16)15-21-11-18(21)5-8-27-24(30)22-12-19-2-1-7-26-23(19)28-22/h1-4,7,10,12,18,21H,5-6,8-9,11,14-15H2,(H,26,28)(H,27,30)/t18-,21+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuse Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from human D3 receptor expressed in HEK293 cell membranes after 1 hr by liquid scintillation counting analysis				J Med Chem 60: 1478-1494 (2017) Article DOI: 10.1021/acs.jmedchem.6b01688 BindingDB Entry DOI: 10.7270/Q2NV9MRV
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50267211 (CHEMBL4068843) Show SMILES O=C(NCC[C@@H]1C[C@H]1CN1CCc2ccc(cc2C1)C#N)c1cc2cccnc2[nH]1 |r| Show InChI InChI=1S/C24H25N5O/c25-13-16-3-4-17-6-9-29(14-20(17)10-16)15-21-11-18(21)5-8-27-24(30)22-12-19-2-1-7-26-23(19)28-22/h1-4,7,10,12,18,21H,5-6,8-9,11,14-15H2,(H,26,28)(H,27,30)/t18-,21+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuse Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from human D2L receptor expressed in HEK293 cell membranes after 1 hr by liquid scintillation counting analysis				J Med Chem 60: 1478-1494 (2017) Article DOI: 10.1021/acs.jmedchem.6b01688 BindingDB Entry DOI: 10.7270/Q2NV9MRV
					More data for this Ligand-Target Pair