BDBM50267302 CHEMBL4066569

SMILES: COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1cc(nc(C)n1)-c1cn(C)c2ccccc12

InChI Key: InChIKey=COHKKDKHQGIOMH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50267302   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50267302 (CHEMBL4066569) Show SMILES COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1cc(nc(C)n1)-c1cn(C)c2ccccc12 Show InChI InChI=1S/C29H35N7O2/c1-8-29(37)33-23-15-24(27(38-7)17-26(23)35(5)14-13-34(3)4)32-28-16-22(30-19(2)31-28)21-18-36(6)25-12-10-9-11-20(21)25/h8-12,15-18H,1,13-14H2,2-7H3,(H,33,37)(H,30,31,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	192	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant cytoplasmic GST-tagged EGFR (668 to 1210 residues) expressed in baculovirus using TK-substrate-biotin preincubated fo...				Eur J Med Chem 135: 12-23 (2017) Article DOI: 10.1016/j.ejmech.2017.04.036 BindingDB Entry DOI: 10.7270/Q28P630H
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